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During 2012 the Secretariat was made aware that the current Good manufacturing practices (GMP) for pharmaceutical products: main principles, published as Annex GOOD MANUFACTURING PRACTICE GUIDELINE. FOR PHARMACEUTICAL PRODUCTS. MAIN PRINCIPLES. First Edition, 2014. Addis Ababa, Ethiopia Pharmaceutical Consultancy Services, All rights reserved. MODERNIZATION OF FDA fda.gov/downloads/Drugs//Guidances/UCM070337.pdf.This document (Guide) is intended to provide guidance regarding good manufacturing practice. (GMP) for the manufacturing of active pharmaceutical Current good manufacturing practice for medical gases: fda.gov/ cder/guidance/3823dft.pdf. • General principles of process validation:

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